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Like most other male mammals, a man's genome typically inherits an X chromosome from his mother and a Y chromosome from his father.The male fetus produces larger amounts of androgens and smaller amounts of estrogens than a female fetus.For males during puberty, testosterone, along with gonadotropins released by the pituitary gland, stimulates spermatogenesis, along with the full sexual distinction of a human male from a human female, while women are acted upon by estrogens and progesterones to produce their sexual distinction from the human male.Sometimes gender scholars will use the phrase "hegemonic masculinity" to distinguish the most dominant form of masculinity from other variants.If a sperm cell carrying an X chromosome fertilizes the egg, the offspring will typically be female (XX); if a sperm cell carrying a Y chromosome fertilizes the egg, the offspring will typically be male (XY).

In the sexually undifferentiated embryo, testosterone stimulates the development of the Wolffian ducts, the penis, and closure of the labioscrotal folds into the scrotum.

The Old English form had a default meaning of "adult male" (which was the exclusive meaning of wer), though it could also signify a person of unspecified gender.

The closely related Old English pronoun man was used just as it is in Modern German to designate "one" (e. The Old English form is derived from Proto-Germanic *mannz, "human being, person", which is also the etymon of German Mann "man, husband" and man "one" (pronoun), Old Norse maðr, and Gothic manna.

This difference in the relative amounts of these sex steroids is largely responsible for the physiological differences that distinguish men from women.

During puberty, hormones which stimulate androgen production result in the development of secondary sexual characteristics, thus exhibiting greater differences between the sexes.

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